RC-106
RC-106 is a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator with anticancer activity. RC-106 has antiproliferative activity against cancer cells including glioblastoma (GB) and multiple myeloma (MM) [1].
Product Specifications
CAS Number
1346216-50-9
UNSPSC
12352005
Target
Proteasome; Sigma Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rc-106.html
Solubility
10 mM in DMSO
Smiles
C/C(C1=CC2=C(C=CC=C2)C=C1)=C\CN3CCC(CC3)CC4=CC=CC=C4
Molecular Formula
C26H29N
Molecular Weight
355.52
References & Citations
[1]Listro R, et al. Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E) -1- (3-Arylbut-2-en-1-yl) -4- (Substituted) Piperazine Derivatives as Potential Anticancer Agents. Front Chem. 2020 Jun 30;8:495.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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