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RC-106

RC-106 is a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator with anticancer activity. RC-106 has antiproliferative activity against cancer cells including glioblastoma (GB) and multiple myeloma (MM) [1].

Product Specifications

CAS Number

1346216-50-9

UNSPSC

12352005

Target

Proteasome; Sigma Receptor

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rc-106.html

Solubility

10 mM in DMSO

Smiles

C/C(C1=CC2=C(C=CC=C2)C=C1)=C\CN3CCC(CC3)CC4=CC=CC=C4

Molecular Formula

C26H29N

Molecular Weight

355.52

References & Citations

[1]Listro R, et al. Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E) -1- (3-Arylbut-2-en-1-yl) -4- (Substituted) Piperazine Derivatives as Potential Anticancer Agents. Front Chem. 2020 Jun 30;8:495.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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