PTP1B-IN-25
Product Specifications
UNSPSC Description
PTP1B-IN-25 (Compound 19) is a PTP1B inhibitor with remarkable antiviral, antibacterial, and antidiabetic activities. PTP1B-IN-25 has IC50 values of 0.37 μM, 8.6 μM, 3.7 μM, and 29 μM against PTP1B, HIV, α-Glucosidase, and methicillin-resistant Staphylococcus aureus (MRSA) respectively[1].
Target Antigen
Bacterial; Fungal; HIV; Phosphatase
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ptp1b-in-25.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCC1=C(C(O)=O)C(O)=CC(OC(C2=C(CCCCCCCCC)C=C(O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)C=C2O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=O)=C1
Molecular Weight
866.98
References & Citations
[1]Chen D, et al. Targeted Discovery of Glycosylated Natural Products by Tailoring Enzyme-Guided Genome Mining and MS-Based Metabolome Analysis. J Am Chem Soc. 2024;146(14):9614-9622.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163463/PTP1B-IN-25-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163463/
Clinical Information
No Development Reported
Curated Selection
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