PTP1B-IN-25

PTP1B-IN-25 (Compound 19) is a PTP1B inhibitor with remarkable antiviral, antibacterial, and antidiabetic activities. PTP1B-IN-25 has IC50 values of 0.37 μM, 8.6 μM, 3.7 μM, and 29 μM against PTP1B, HIV, α-Glucosidase, and methicillin-resistant Staphylococcus aureus (MRSA) respectively[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial; Fungal; HIV; Phosphatase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ptp1b-in-25.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCC1=C(C(O)=O)C(O)=CC(OC(C2=C(CCCCCCCCC)C=C(O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)C=C2O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=O)=C1

Molecular Formula

C44H66O17

Molecular Weight

866.98

References & Citations

[1]Chen D, et al. Targeted Discovery of Glycosylated Natural Products by Tailoring Enzyme-Guided Genome Mining and MS-Based Metabolome Analysis. J Am Chem Soc. 2024;146 (14) :9614-9622.