Properdistatin

Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma[1].

Product Specifications

CAS Number

[945373-85-3]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/properdistatin.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C(CN)=O)N[C@H](C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](CS)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34

Molecular Formula

C89H149N33O27S2

Molecular Weight

2177.47

References & Citations

[1]Gaustad JV, et al. Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression. Oncotarget. 2016 Nov 22;7 (47) :76806-76815.