ONO-8809
Product Specifications
UNSPSC Description
ONO-8809 is a Thromboxane A2 receptor antagonist. ONO-8809 inhibits the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ono-8809.html
Smiles
O=S(NC[C@H]1[C@@H]([C@]2([H])C[C@@]1([H])CC2)/C=C\CCCC(OCCCCCCCCCC)=O)(C3=CC=C(C=C3)Br)=O
Molecular Weight
596.66
References & Citations
[1]Kurosawa M, et al. Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs. Clin Exp Allergy. 1993 Oct;23(10):843-50.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116560/ONO-8809-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116560/
Clinical Information
No Development Reported
CAS Number
123288-47-1
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