ONO-8809

ONO-8809 is a Thromboxane A2 receptor antagonist. ONO-8809 inhibits the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner[1].

Product Specifications

CAS Number

[123288-47-1]

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ono-8809.html

Smiles

O=S(NC[C@H]1[C@@H]([C@]2([H])C[C@@]1([H])CC2)/C=C\CCCC(OCCCCCCCCCC)=O)(C3=CC=C(C=C3)Br)=O

Molecular Formula

C30H46BrNO4S

Molecular Weight

596.66

References & Citations

[1]Kurosawa M, et al. Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs. Clin Exp Allergy. 1993 Oct;23 (10) :843-50.