Xanthurenic acid-d4

Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].

Product Specifications

CAS Number

[1329611-28-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite; mGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

99.09

Solubility

10 mM in DMSO|DMSO : 8.93mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=C([2H])C([2H])=C([2H])C2=C1N=C(C(O)=O)C([2H])=C2O

Molecular Formula

C10H3D4NO4

Molecular Weight

209.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Copeland CS, et al. Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42.