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Human IL-28A Protein, His tag (Animal-Free)

Interleukin 28A (IL-28A) predicts a molecular mass of 22.3 kDa. IL-28 comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an antiviral state by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G.

Product Specifications

Background

Interleukin 28A (IL-28A) predicts a molecular mass of 20.6 kDa. IL-28 comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an antiviral state by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G

Product Name Alternative

Interleukin 28A, IFN-λ2, IL28, IL28A

Gene ID

282616

Accession Number

Q8IZJ0

Tag

IL-28A

Type

Cytokines and proteins

Applications

His tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measure by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus. The ED₅₀ for this effect is <20 ng/mL.

Molecular Formula

20.60 kDa

Molecular Weight

20.60 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin :< 0.1 EU per 1 μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA,10% FBS or 0.1%BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human IL-28A consists of 174 amino acids and predicts a molecular mass of 20.6 kDa.

Formulation

Lyophilized from sterile PBS, pH 8.0.

Applications Notes

Human

Other Product Names

IL28A, IL-28A, IL 28A, interleukin 28A, IFN-λ2, IL28

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.

Preparation

E.coli

Accession Number URL

https://www.uniprot.org/uniprotkb/Q8IZJ0/entry#similar_proteins

AA Sequence

Amino acid sequence derived from Human IL-28A (Pro27-Val200) (Q8IZJ0) was expressed with 6xHis tag at the C-terminus.

Available Sizes

Frequently Asked Questions

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