Fluorogenic Caspase (Apopain) Substrate 1f-z

<strong>Fluorogenic Caspase (Apopain) Substrate 1f-z</strong>_x000D_ <strong>Catalog number:</strong> B2011408_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 821.7 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Caspase 3 (Apopain) Substrate 1f-z, fluorogenic_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Xiong C, Lu W, Zhang R, Tian M, Tong W, Gelovani J, Li C. Cell-permeable [99mTc(CO3)]-labeled fluorogenic caspase 3 substrate for dual-modality detection of apoptosis Chemistry. 2009 Sep 14;15(36):8979-84._x000D_ 2: Mackay M, Pérez-López AM, Bradley M, Lilienkampf A. Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates Mol Biosyst. 2016 Mar;12(3):693-6._x000D_ 3: Pérez-López AM, Soria-Gila ML, Marsden ER, Lilienkampf A, Bradley M. Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells PLoS One. 2016 May 11;11(5):e0153209._x000D_ 4: Lee BW, Johnson GL, Hed SA, Darzynkiewicz Z, Talhouk JW, Mehrotra S. DEVDase detection in intact apoptotic cells using the cell permeant fluorogenic substrate, (z-DEVD)2-cresyl violet Biotechniques. 2003 Nov;35(5):1080-5._x000D_ 5: Kitevska T, Roberts SJ, Pantaki-Eimany D, Boyd SE, Scott FL, Hawkins CJ. Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate Biosci Rep. 2014 Apr 1;34(2):e00100._x000D_ 6: Poreba M, Rut W, Groborz K, Snipas SJ, Salvesen GS, Drag M. Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells Cell Death Differ. 2019 Dec;26(12):2695-2709._x000D_ 7: He L, Ye S, Fang J, Zhang Y, Cui C, Wang A, Zhao Y, Shi H. Real-Time Visualization of Embryonic Apoptosis Using a Near-Infrared Fluorogenic Probe for Embryo Development Evaluation Anal Chem. 2021 Sep 7;93(35):12122-12130._x000D_ 8: Castro MM, Fuah J, Ali M, Sung M, Schulz J, Kondo MY, Fan X, Holt A, Schulz R. Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2 Biochem Pharmacol. 2013 Aug 15;86(4):469-75._x000D_ 9: Fuente-Garcia C, Sentandreu E, Aldai N, Sentandreu MA. Optimization of a fluorogenic assay to determine caspase 3/7 activity in meat extracts Food Sci Technol Int. 2022 Mar;28(2):128-134._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20134429">10: Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis Nat Protoc. 2010 Feb;5(2):294-302. </a>_x000D_ _x000D_ <strong>Products Related to Fluorogenic Caspase (Apopain) Substrate 1f-z can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>