BDF 9148
BDF 9148 is a sodium-channel activator with antiarrhythmic properties that produces a significant CAMP-independent positive inotropic effect in left ventricular myocardium from failing hearts. BDF 9148 is promising for research of myocardial failure[1].
Product Specifications
CAS Number
120838-62-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bdf-9148.html
Smiles
N#CC(N1)=CC2=C1C=CC=C2OCC(O)COC3CN(C(C4=CC=CC=C4)C5=CC=CC=C5)C3
Molecular Formula
C28H27N3O3
Molecular Weight
453.53
References & Citations
[1]Schwinger RH, et al. Evidence for a sustained effectiveness of sodium-channel activators in failing human myocardium. J Mol Cell Cardiol. 1991 Apr;23 (4) :461-71.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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