MitoTEMPOL
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2[1].
Product Specifications
CAS Number
[1101113-39-6]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mitotempol.html
Purity
99.0
Solubility
DMF : 50 mg/mL (ultrasonic; warming) |DMSO : 50 mg/mL (ultrasonic; warming) |Ethanol : 50 mg/mL (ultrasonic; warming)
Smiles
[O]N1C(C)(CC(CC1(C)C)OCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
Molecular Formula
C32H42BrNO2P?
Molecular Weight
583.56
References & Citations
[1]Trnka J, et al. A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria. Free Radic Biol Med. 2008;44 (7) :1406-1419.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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