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Cathepsin D Rabbit mAb [KD Validated] Antibody

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Product Specifications

Product Name Alternative

CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311

UniProt

P07339

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cathepsin D

Clonality

Monoclonal

Conjugation

Unconjugated

Purification

Affinity-chromatography

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:20

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

FC, ICC, IHC, IP, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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