Tenofovir diphosphate (disodium)

Tenofovir diphosphate disodium is an antiretroviral agent. Tenofovir diphosphate disodium is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM) . Tenofovir diphosphate disodium can be used for the research of AIDS[1].

Product Specifications

CAS Number

[2738719-07-6]

Product Name Alternative

TFV-DP (disodium)

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tenofovir-diphosphate-disodium.html

Purity

99.42

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

C[C@@H](OC[P](O[P](O[P](O[Na])(O[Na])=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1

Molecular Formula

C9H14N5Na2O10P3

Molecular Weight

491.14

References & Citations

[1]Birkus G, et al. Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases alpha, delta, and epsilon*. Antimicrob Agents Chemother. 2002 May;46 (5) :1610-3.