Cyclin D1 Rabbit mAb [KD Validated] Antibody
Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
Product Specifications
Product Name Alternative
CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1
UniProt
P24385
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Cyclin D1
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:100 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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