Chk2 Rabbit mAb [KD Validated] Antibody
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Product Specifications
Product Name Alternative
CHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2
UniProt
O96017
Reactivity
Human
Immunogen
A synthesized peptide derived from human Chk2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB 1:10000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Dictyostelium discoideum Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN (cnrN), partial
SCTR Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)