Chk2 Rabbit mAb [KD Validated] Antibody
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Product Specifications
Product Name Alternative
CHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2
UniProt
O96017
Reactivity
Human
Immunogen
A synthesized peptide derived from human Chk2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB 1:10000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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