5-Fluoroorotic Acid Monohydrate (5-FOA)

<strong>5-Fluoroorotic Acid Monohydrate (5-FOA)</strong>_x000D_ <strong>Catalog number:</strong> B2015500_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 g_x000D_ <strong>Molecular Weight or Concentration:</strong> 192.10 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 5-Fluorouracil-4-carboxylic acid_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Boeke JD, Trueheart J, Natsoulis G, Fink GR. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics Methods Enzymol. 1987;154:164-75._x000D_ 2: Rathod PK, Khatri A, Hubbert T, Milhous WK. Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro Antimicrob Agents Chemother. 1989 Jul;33(7):1090-4._x000D_ 3: Nakazawa T, Tsuzuki M, Irie T, Sakamoto M, Honda Y. Marker recycling via 5-fluoroorotic acid and 5-fluorocytosine counter-selection in the white-rot agaricomycete Pleurotus ostreatus Fungal Biol. 2016 Sep;120(9):1146-55._x000D_ 4: Yano T, Sanders C, Catalano J, Daldal F. sacB-5-Fluoroorotic acid-pyrE-based bidirectional selection for integration of unmarked alleles into the chromosome of Rhodobacter capsulatus Appl Environ Microbiol. 2005 Jun;71(6):3014-24._x000D_ 5: Cuellar A, Alcolea Palafox M, Rastogi VK, Kiefer W, Schlücker S, Rathor SK. FT-IR and FT-Raman spectra of 5-fluoroorotic acid with solid state simulation by DFT methods Spectrochim Acta A Mol Biomol Spectrosc. 2014 Nov 11;132:430-45._x000D_ 6: Schneider AG, Schmalle HW, Arod F, Dubler E. The interaction of 5-fluoroorotic acid with transition metals: synthesis and characterisation of Ni(II), Cu(II) and Zn(II) complexes J Inorg Biochem. 2002 Apr 28;89(3-4):227-36._x000D_ 7: Krooth RS, Hsiao WL, Potvin BW. Resistance to 5-fluoroorotic acid and pyrimidine auxotrophy: a new bidirectional selective system for mammalian cells Somatic Cell Genet. 1979 Sep;5(5):551-69._x000D_ 8: WAGNER NJ, HEIDELBERGER C. Some effects of 5-fluoroorotic acid and 5-fluorouracii on the soluble acid of rat liver Biochim Biophys Acta. 1962 Sep 17;61:373-9._x000D_ 9: Eriksson G, Stenram U. The effect of 5-fluoroorotic acid on the early labelling of nucleotides and RNA in whole liver and of RNA in subnuclear fractions in rats given 3H-orotic acid Adv Exp Med Biol. 1984;165 Pt A:543-5._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/13523598">10: CHAUDHURI NK, MONTAG BJ, HEIDELBERGER C. Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo Cancer Res. 1958 Apr;18(3):318-28.</a>_x000D_ _x000D_ <strong>Products Related to 5-Fluoroorotic Acid Monohydrate (5-FOA) can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>