PARK7 Rabbit mAb [KD Validated] Antibody
Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress.
Product Specifications
Product Name Alternative
Protein DJ-1; SP22; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7; PARK7
UniProt
Q99497
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human PARK7
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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