Isovitexin

Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.

Product Specifications

CAS Number

[38953-85-4]

Product Name Alternative

Saponaretin; Homovitexin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

JNK; NF-κB

Type

Natural Products

Related Pathways

MAPK/ERK Pathway; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Isovitexin.html

Purity

99.90

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

OC1=C(C2=O)C(OC(C3=CC=C(O)C=C3)=C2)=CC(O)=C1[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO

Molecular Formula

C21H20O10

Molecular Weight

432.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Lv H, et al. Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways. Int J Biol Sci. 2016 Jan 1;12 (1) :72-86.|[2]Hu JJ, et al. Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. Microb Pathog. 2018 Mar 29;119:86-92.