Cdc23/APC8 Rabbit mAb [KD Validated] Antibody
Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16) . APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.
Product Specifications
Product Name Alternative
CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8
UniProt
Q9UJX2
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Cdc23/APC8
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:100
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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