Bmi1 Rabbit mAb [KD Validated] Antibody
The polycomb group (PcG) of proteins contributes to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle arrest. PcG proteins exist in two complexes that cooperate to maintain long-term gene silencing through epigenetic chromatin modifications. The first complex, EED-EZH2, is recruited to genes by DNA-binding transcription factors and methylates histone H3 on Lys27.
Product Specifications
Product Name Alternative
BMI1 ; Polycomb complex protein BMI 1; RING finger protein 51; RNF51; PCGF4
UniProt
P35226
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human Bmi1
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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