C-Jun (Phospho Ser249) rabbit pAb
Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. similarity: Belongs to the bZIP family. similarity: Belongs to the bZIP family. Jun subfamily. similarity: Contains 1 bZIP domain. subunit: Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.
Product Specifications
Background
Product Name Alternative
Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39)
UniProt
P05412
Swiss Prot
P05412
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human c-Jun (Phospho Ser249)
Target
C-JUN
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
39-42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
39-42kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39)
Gene ID (Human)
3725
Available Sizes
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