C-Jun (Phospho Ser249) rabbit pAb
Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. similarity: Belongs to the bZIP family. similarity: Belongs to the bZIP family. Jun subfamily. similarity: Contains 1 bZIP domain. subunit: Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.
Product Specifications
Background
Synonyms
Transcription factor AP-1 (Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39)
Gene ID
3725
UniProt
P05412
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human c-Jun (Phospho Ser249)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Molecular Weight
39-42kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20155-1.pdf
Observed Molecular Weight
39 - 42 kD
Subcellular Location
Nucleus.
Other Product Names
Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39)
Gene ID (Human)
3725
SwissProt (Human)
P05412
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
