Metallo-β-lactamase-IN-14
Product Specifications
UNSPSC Description
Metallo-β-lactamase-IN-14 (Compound 17e) is a Metallo-β-Lactamase inhibitor. Metallo-β-lactamase-IN-14 shows inhibition activity against VIM-1 and VIM-2. Metallo-β-lactamase-IN-14 has antibacterial activity against Gram-negative (GN) bacteria and P. aeruginosa[1].
Target Antigen
Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/metallo-β-lactamase-in-14.html
Solubility
10 mM in DMSO
Smiles
O=S(N)(C1=C(C2=NN=NN2)C(C3=C4N=C(N)SC4=CC=C3)=CC=C1CC5CCNCC5)=O
Molecular Weight
470.57
References & Citations
[1]Dong S, et al. Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J Med Chem. 2024 Feb 22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163339/Metallo-β-lactamase-IN-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163339/
Clinical Information
No Development Reported
CAS Number
1802367-43-6
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