USP1-IN-3
USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of [1].
Product Specifications
CAS Number
[2821749-58-8]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp1-in-3.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C2=NC3=C(N(C)C=C3CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4)C=N2)C(C6CC6)=NC=N1
Molecular Formula
C27H24F3N7O
Molecular Weight
519.52
References & Citations
[1]Scott Throner, et al. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer. Patent. WO2022174184A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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