Native Mouse Apotransferrin

<strong>Native Mouse Apotransferrin</strong>_x000D_ <strong>Catalog number:</strong> B2017414_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Serotransferrin, beta-1-metal-binding globulin, Liver regeneration-related protein LRRG03, siderophilin, TRF_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Biedroń R, Konopiński MK, Marcinkiewicz J, Józefowski S. Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages PLoS One. 2015 Apr 7;10(4):e0123293._x000D_ 2: García-Serran A, Ordoño J, DeGregorio-Rocasolano N, Melià-Sorolla M, Odendaal K, Martí-Sistac O, Gasull T. Targeting Pro-Oxidant Iron with Exogenously Administered Apotransferrin Provides Benefits Associated with Changes in Crucial Cellular Iron Gate Protein TfR in a Model of Intracerebral Hemorrhagic Stroke in Mice Antioxidants (Basel). 2023 Oct 31;12(11):1945._x000D_ 3: Mangano K, Fagone P, Di Mauro M, Ascione E, Maiello V, Milicic T, Jotic A, Lalic NM, Saksida T, Stojanovic I, Selmi C, Farina C, Stosic-Grujicic S, Meroni P, Nicoletti F. The immunobiology of apotransferrin in type 1 diabetes Clin Exp Immunol. 2012 Sep;169(3):244-52._x000D_ 4: Chen-Roetling J, Chen L, Regan RF. Apotransferrin protects cortical neurons from hemoglobin toxicity Neuropharmacology. 2011 Feb-Mar;60(2-3):423-31._x000D_ 5: Sheokand N, Malhotra H, Chauhan AS, Kumar M, Chaudhary S, Patidar A, Boradia VM, Raje CI, Raje M. Reverse overshot water-wheel retroendocytosis of apotransferrin extrudes cellular iron J Cell Sci. 2016 Feb 15;129(4):843-53._x000D_ 6: Mattera VS, Pereyra Gerber P, Glisoni R, Ostrowski M, Verstraeten SV, Pasquini JM, Correale JD. Extracellular vesicles containing the transferrin receptor as nanocarriers of apotransferrin J Neurochem. 2020 Nov;155(3):327-338._x000D_ 7: Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ. Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice Blood. 2017 Mar 16;129(11):1514-1526._x000D_ 8: Tsyplenkova S, Charlebois E, Fillebeen C, Pantopoulos K. Excess of circulating apotransferrin enhances dietary iron absorption in mice Blood. 2024 Jul 4;144(1):117-121._x000D_ 9: Saksida T, Miljkovic D, Timotijevic G, Stojanovic I, Mijatovic S, Fagone P, Mangano K, Mammana S, Farina C, Ascione E, Maiello V, Nicoletti F, Stosic-Grujicic S. Apotransferrin inhibits interleukin-2 expression and protects mice from experimental autoimmune encephalomyelitis J Neuroimmunol. 2013 Sep 15;262(1-2):72-8._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25616571">10: Gelderman MP, Baek JH, Yalamanoglu A, Puglia M, Vallelian F, Burla B, Vostal J, Schaer DJ, Buehler PW. Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice Haematologica. 2015 May;100(5):611-22. </a>_x000D_ _x000D_ <strong>Products Related to Native Mouse Apotransferrin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>