GW837016X
Product Specifications
UNSPSC Description
GW837016X (NEU-391) is an orally active ErbB-2 kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis[1].
Target Antigen
EGFR; Paraptosis
Type
Reference compound
Related Pathways
Apoptosis;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gw837016x.html
Smiles
FC1=CC(COC2=CC=C(NC3=C4C(C=C(C#C[C@H]5NCCC5)S4)=NC=N3)C=C2Cl)=CC=C1
Molecular Weight
478.97
References & Citations
[1]Woodring JL, et al. Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation. ACS Med Chem Lett. 2018 Sep 4;9(10):996-1001.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129288/GW837016X-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129288/
Clinical Information
No Development Reported
CAS Number
833473-68-0
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