Dinoxyline

Dinoxyline is a potent agonist at dopamine receptors (Ki = 7 nM, 6 nM, 5 nM, 43 nM for D1, D2, D3 and D4) . Dinoxyline can be utilized in neurological research[1].

Product Specifications

CAS Number

[757176-96-8]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dinoxyline.html

Smiles

OC1=CC=C2C(OC3=CC=CC4=C3C2CNC4)=C1O

Molecular Formula

C15H13NO3

Molecular Weight

255.27

References & Citations

[1]Fowler JC, et al. Receptor conformations involved in dopamine D (2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations. Mol Pharmacol. 2012 Jun;81 (6) :820-31.