Larixyl acetate (Standard)

Larixyl acetate (Standard) is the analytical standard of Larixyl acetate. This product is intended for research and analytical applications. Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction[1][2].

Product Specifications

CAS Number

[4608-49-5]

UNSPSC

12352211

Target

HPV; Reference Standards; TRP Channel

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/larixyl-acetate-standard.html

Smiles

CC(CCC1)(C)[C@]([C@@]1(C)[C@H]2CC[C@](C)(O)C=C)([H])[C@@H](OC(C)=O)CC2=C

Molecular Formula

C22H36O3

Molecular Weight

348.52

References & Citations

[1]Urban N, et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor. Mol Pharmacol. 2016 Jan;89 (1) :197-213. |[2]Chen X, et al. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. J Neuroinflammation. 2019 Jan 31;16 (1) :21.