Quinotolast sodium
Quinotolast sodium in the concentration range of 1-100 μg/mL inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner.
Product Specifications
CAS Number
101193-62-8
Product Name Alternative
FR71021
UNSPSC
12352005
Target
Histamine Receptor; Leukotriene Receptor; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Quinotolast_(sodium).html
Purity
98.38
Solubility
DMSO : 115 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NN=NN1)C2=CC(OC3=CC=CC=C3)=C4N(C2=O)C=CC=C4.[Na]
Molecular Formula
C17H12N6NaO3
Molecular Weight
371.31
References & Citations
[1]Okayama Y, et al. Inhibition of histamine and eicosanoid release from dispersed human lung cells in vitro byquinotolast. Jpn J Pharmacol. 1995 Dec;69 (4) :375-80.|[2]Kobayashi K, et al. Effects of quinotolast, a new orally active antiallergic drug, on experimental allergic models. Jpn J Pharmacol. 1993 Sep;63 (1) :73-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DP; LTC4/CysLT2
Available Sizes
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