STAT3 Rabbit mAb [KD Validated] Antibody
Transcription factor that binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Product Specifications
Product Name Alternative
APRF; Acute-phase response factor; Signal transducer and activator of transcription 3; STAT3; HIES
UniProt
P40763
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human STAT3
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
