Wnt5a Rabbit mAb [KD Validated] Antibody
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
Product Specifications
Product Name Alternative
HWNT5A; Protein Wnt5a; Wingless type MMTV integration site family member 5A; WNT 5A protein; WNT 5A protein precursor; WNT5A
UniProt
P41221
Reactivity
Human
Immunogen
A synthesized peptide derived from human Wnt5a
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Affinity-chromatography
Dilution
WB 1:500~1:1000 ICC/IF 1:50~1:200 FC 1:20
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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