Elziverine
Elziverine (Ro 22-4839) is a brain circulation improvement agent with vasospasm antispasmodic effects. Elziverine is a calmodulin antagonist. Elziverine inhibits erythrocyte cell membrane rupture, platelet aggregation and lipid peroxidation[1].
Product Specifications
CAS Number
95520-81-3
Product Name Alternative
Ro 22-4839
UNSPSC
12352005
Target
Calmodulin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/elziverine.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C(CN2CCN(CC2)C3=C(OC)C=CC=C3)=CN=C4CC5=CC=C(C(OC)=C5)OC)=C4C=C1OC
Molecular Formula
C32H37N3O5
Molecular Weight
543.65
References & Citations
[1]Nakajima T, et al. Calmodulin antagonistic action of the cerebral circulation improver 6,7-dimethoxy-1- (3,4-dimethoxybenzyl) -4- ([4- (2-methoxyphenyl) -1-piperazinyl]methyl) isoquinoline. Arzneimittelforschung. 1987 Jun;37 (6) :674-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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