Ebsulfur
Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis[1].
Product Specifications
CAS Number
[2527-03-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebsulfur.html
Purity
99.99
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=CC=C2)SC3=C1C=CC=C3
Molecular Formula
C13H9NOS
Molecular Weight
227.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Lu J, et al. Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei. J Biol Chem. 2013 Sep 20;288 (38) :27456-27468.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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