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TDP43 Rabbit mAb [KD Validated] Antibody

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

Product Specifications

Product Name Alternative

ALS10; TAR DNA binding protein 43; TARDBP; TDP43

UniProt

Q13148

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from TDP43

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Neuroscience

Purification

Affinity-chromatography

Dilution

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

FC, ICC, IHC, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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