Clioxanide
Product Specifications
UNSPSC Description
Clioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide[1].
Target Antigen
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
infection
Assay Protocol
https://www.medchemexpress.com/clioxanide.html
Smiles
CC(OC1=C(I)C=C(I)C=C1C(NC2=CC=C(Cl)C=C2)=O)=O
Molecular Weight
541.51
References & Citations
[1]COMPARATIVE EFFICIENCY OF HEXACHLOROETHANE AND CLIOXANIDE AGAINST FASCIOLA HEPATICA IN THE RAT
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114969/Clioxanide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114969/
Clinical Information
No Development Reported
CAS Number
14437-41-3
Curated Selection
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