Clioxanide
Clioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide[1].
Product Specifications
CAS Number
[14437-41-3]
Product Name Alternative
NSC 233846; SYD 230; Tremerad
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/clioxanide.html
Smiles
CC(OC1=C(I)C=C(I)C=C1C(NC2=CC=C(Cl)C=C2)=O)=O
Molecular Formula
C15H10ClI2NO3
Molecular Weight
541.51
References & Citations
[1]COMPARATIVE EFFICIENCY OF HEXACHLOROETHANE AND CLIOXANIDE AGAINST FASCIOLA HEPATICA IN THE RAT
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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