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CRTC3 Rabbit mAb [KD Validated] Antibody

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.

Product Specifications

Product Name Alternative

CRTC3; TORC3

UniProt

Q6UUV7

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human CRTC3

Clonality

Monoclonal

Conjugation

Unconjugated

Purification

Affinity-chromatography

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IHC, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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