PPAR α (Phospho Ser21) rabbit pAb
Function: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. online information: Peroxisome proliferator-activated receptor entry, similarity: Belongs to the nuclear hormone receptor family. NR1 subfamily. similarity: Contains 1 nuclear receptor DNA-binding domain. subunit: Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13. tissue specificity: Skeletal muscle, liver, heart and kidney.
Product Specifications
Background
Product Name Alternative
Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)
UniProt
Q07869
Swiss Prot
Q07869
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human PPAR α (Phospho Ser21)
Target
PPAR α
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
52kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
52kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)
Gene ID (Human)
5465
Available Sizes
Frequently Asked Questions
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