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Phospho-MSK1 (Thr581) rabbit mAb PE conjugate Antibody

MSK1 (mitogen and stress activated protein kinase 1, phospho MSK1) is activated by Erk in response to growth factors and by and p38 in response to cellular stress (1) . MSK1 is similar to RSK1 in that it has two kinase domains and a connecting regulatory linker region (2) . S364/S381 phosphorylation activates RSK1 (3), which is analogous to residues S360 and S376 of MSK1, which may be important for phospho MSK1 activity.

Product Specifications

Product Name Alternative

Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5

UniProt

O75582

Reactivity

Human, Mouse, Rat

Cross Reactivity

Predicted to work with mouse, rat and other homologues.

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1

Clonality

Monoclonal

Clone

BC7

Conjugation

PE

Field of Research

Signal Transduction

Purification

Protein A+G

Dilution

For flow cytometric staining, the suggested use of this reagent is 5 μL per million cells or 5 μL per 100 μL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.

Form

Liquid

Storage Conditions

2-8°C

Notes

For research use only.

Tested Applications

FC

Host or Source

Rabbit

Preservative

1X PBS, 0.09% NaN3, 0.2% rAlbumin

Isotype

Rabbit IgG1k

Available Sizes

Frequently Asked Questions

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