Phospho-PLCg1 (Tyr783) rabbit mAb Antibody
The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositolphosphate to inositol triphosphate and diacylglycerol. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate diacylglycerols (DAGs) and water-soluble phosphorylated derivatives, such as inositol 1,4,5-triphosphate (IP3) .„ÄÄWithin the PLC family, PLCg is the only member that contains SH2 and SH3 domains, necessary for phospho PLCg activation. Phospho PLCg, upon activation, can interact with receptor tyrosine kinases.
Product Specifications
Product Name Alternative
UniProt
P19174
Reactivity
Human, Mouse
Cross Reactivity
Predicted to work with mouse, rat, and other homologues.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
Clonality
Monoclonal
Clone
BE6
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein A+G
Concentration
0.5 mg/mL
Dilution
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC
Host or Source
Rabbit
Preservative
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% rAlbumin
Isotype
Rabbit IgG1k
Available Sizes
Frequently Asked Questions
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