Phospho-Ship2 (Tyr1135) rabbit mAb PE conjugate Antibody
Ship2 (SH2-containing inositol phosphatase 2, phospho Ship2) is a homolog of Ship1. Ship2 is highly expressed in the heart, in skeletal muscle, and in the placenta (1) . SHIP2 negatively regulates insulin signaling (2), and Ship2 polymorphisms have been linked to hyperglycemia (3) . Phospho Ship2 has been identified as a potential therapeutic target for the treatment of obesity and type 2 diabetes (4,5) . The Ship2 residue Tyr1135 is phosphorylated in human cancer cells (6-8) .
Product Specifications
Product Name Alternative
UniProt
O15357
Reactivity
Human, Mouse
Cross Reactivity
Predicted to work with mouse, rat, and other homologues.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2
Clonality
Monoclonal
Clone
B3F4
Conjugation
PE
Field of Research
Signal Transduction
Purification
Protein A+G
Dilution
Form
Liquid
Storage Conditions
2-8°C
Notes
For research use only.
Tested Applications
FC
Host or Source
Rabbit
Preservative
1X PBS, 0.09% NaN3, 0.2% rAlbumin
Isotype
Rabbit IgG1k
Available Sizes
Frequently Asked Questions
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