Antiflammin-1

Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS) . Antiflammin-1 is a derivative of uteroglobin. Antiflammin-1 has anti-inflammatory and antifibrotic actions in bleomycin (HY-108345) -induced lung injury[1][2][3].

Product Specifications

CAS Number

[118850-71-8]

Product Name Alternative

Uteroglobin (39-47)

UNSPSC

12352209

Target

Interleukin Related

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/antiflammin-1.html

Solubility

H2O

Smiles

OC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCSC)NC([C@H](CCC(N)=O)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C45H82N12O14S2

Molecular Weight

1079.33

References & Citations

[1]Liu W, et al. Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice. Respir Res. 2013 Oct 8;14 (1) :101.|[2]Camussi G, et al. Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactions. J Exp Med. 1990 Mar 1;171 (3) :913-27. |[3]Martínez Leo EE, et al. Biopeptides with antioxidant and anti-inflammatory potential in the prevention and treatment of diabesity disease. Biomed Pharmacother. 2016 Oct;83:816-826.