Phospho-mTOR (Ser2448) rabbit mAb Antibody
MTOR, m ammalian t arget o f r apamycin, is a Serine/Threonine protein kinase (1-2) that functions as an amino acid and ATP sensor to balance cell growth and nutrient availability (3-4) . When sufficient nutrients are available, mTOR transmits a positive signal to p70 S6 kinase and participates in the inactivation of 4E-BP1 (5) . mTOR plays a key role in homeostasis and cell growth, and phospho mTOR may be abnormally regulated in tumors. mTOR is a potential target for anti-cancer therapy (6) .
Product Specifications
Product Name Alternative
UniProt
P42345
Reactivity
Human, Mouse
Cross Reactivity
Predicted to work with mouse, rat and other homologues.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR
Clonality
Monoclonal
Clone
BG33
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein A+G
Concentration
0.5 mg/mL
Dilution
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC
Host or Source
Rabbit
Preservative
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% rAlbumin
Isotype
Rabbit IgG1k
Available Sizes
Frequently Asked Questions
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