Phospho-c-Fos (Ser32) rabbit mAb Antibody
C-FOS belongs to the Fos family of nuclear oncogenes which include Fos B, Fos-related antigen 1 (FRA1), Fos-related antigen 2 (FRA2) in addition to c-Fos (1) . Activator Protein-1 (AP-1) is formed upon dimerization of Fos proteins with Jun protiens (c-Jun, Jun B, and JunD) (2,3) . AP-1 is considered a transcription factor that binds to TRE/AP-1 elements and activates transcription. ERK5 is involved with c-Fos phosphorylation at Ser32 and Thr232 which increase c-Fos stability and its nuclear translocation.
Product Specifications
Product Name Alternative
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, G0S7
UniProt
P01100
Reactivity
Human, Mouse, Rat
Cross Reactivity
Predicted to work with mouse, rat and other homologues.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser32 of human phospho c-Fos
Clonality
Monoclonal
Clone
BDC1
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein A+G
Concentration
0.5 mg/mL
Dilution
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC
Host or Source
Rabbit
Preservative
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% rAlbumin
Isotype
Rabbit IgG1k
Available Sizes
Frequently Asked Questions
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