Phospho-MCM2 (Ser139) rabbit mAb Antibody
The members of minichromosome maintenance (McM) protein family 2-7 were originally identified as a group of proteins essential for DNA replication (chromosomal maintenance (1,2) . They share common sequence homology to each other in their nulceotide-binding domains and are distinct subgroup of the large AAA ATPase family, which are required for the initiation and elongation of DNA replication. It has been reported that Cdc7/Dbf4 phospohrylates MCM2 during G1/S cell cycle which coincides with the intiation of DNA replication (3,4)
Product Specifications
Product Name Alternative
DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, CCNL1, CDCL1, KIAA0030
UniProt
P49736
Reactivity
Human, Mouse, Rat
Cross Reactivity
Predicted to work with mouse, rat and other homologues.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho MCM2
Clonality
Monoclonal
Clone
BD34
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Protein A+G
Concentration
0.5 mg/mL
Dilution
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, WB
Host or Source
Rabbit
Preservative
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% rAlbumin
Isotype
Rabbit IgG1k
Available Sizes
Frequently Asked Questions
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