FLT3 ligand-2

FLT3 ligand-2 is a Ligand for Target Protein for PROTAC. FLT3 ligand-2 can be used to synthesize PROTAC FLT-3 degrader 1 (HY-114323) [1].

Product Specifications

CAS Number

[950769-51-4]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/flt3-ligand-2.html

Smiles

OC1=CC2=C(N3C(S2)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3)C=C1

Molecular Formula

C23H21N5O3S

Molecular Weight

447.51

References & Citations

[1]Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140 (48) :16428-16432.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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