FLT3 ligand-2
FLT3 ligand-2 is a Ligand for Target Protein for PROTAC. FLT3 ligand-2 can be used to synthesize PROTAC FLT-3 degrader 1 (HY-114323) [1].
Product Specifications
CAS Number
[950769-51-4]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-ligand-2.html
Smiles
OC1=CC2=C(N3C(S2)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3)C=C1
Molecular Formula
C23H21N5O3S
Molecular Weight
447.51
References & Citations
[1]Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140 (48) :16428-16432.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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