Dusigitumab Antibody
Dusigitumab (MEDI573) is a fully human monoclonal antibody targeting both IGF1 and IGF2. It inhibits IGF-1R phosphorylation with IC50 values of 0.97 μg/mL and 0.2 μg/mL against IGF1 and IGF2, respectively. This agent is utilized in cancer research, including in vitro cell signaling studies and in vivo xenograft models.
Product Specifications
Product Name Alternative
IGF1R, MEDI573
Target
IGF-1R
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
5.55 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
144.22 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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