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Dusigitumab Antibody

Dusigitumab (MEDI573) is a fully human monoclonal antibody targeting both IGF1 and IGF2. It inhibits IGF-1R phosphorylation with IC50 values of 0.97 μg/mL and 0.2 μg/mL against IGF1 and IGF2, respectively. This agent is utilized in cancer research, including in vitro cell signaling studies and in vivo xenograft models.

Product Specifications

Product Name Alternative

IGF1R, MEDI573

Target

IGF-1R

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Signal Transduction

Concentration

5.55 mg/mL

Purity

95.00% (May vary between batches)

Molecular Weight

144.22 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

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