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Empasiprubart Antibody

Empasiprubart (ARGX-117) is a humanized inhibitory monoclonal antibody that binds the C2 protein's Sushi-2 domain, blocking C3 proconvertase formation to inhibit the classical and lectin complement pathways. It has demonstrated efficacy in in vivo models of autoimmune hemolytic anemia and antibody-mediated transplant rejection, and is used in related in vitro immunological research.

Product Specifications

Product Name Alternative

ARGX-117

Target

Complement System

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Concentration

10.8 mg/mL

Purity

≥95% (May vary between batches)

Molecular Weight

~150 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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