Galanin (1-13) -spantide I
Galanin (1-13) -spantide I is a chimeric peptide composed of the N-terminal fragment of galanin (amino acids 1-13) and spantide, a known substance P receptor antagonist. Galanin (1-13) -spantide I has a high affinity for spinal galanin receptor (Kd=1.16 nM) . Galanin (1-13) -spantide I can be used to study the effects of galanin on feeding behavior[1][2].
Product Specifications
CAS Number
143868-20-6
UNSPSC
12352209
Target
Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/galanin-1-13-spantide-i.html
Smiles
CC(C)C[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=CC=CC=C12)NC([C@H](CC3=CC=CC=C3)NC([C@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CCCCN)NC([C@H]5N(CCC5)C([C@@H](CCCNC(N)=N)NC([C@H]6N(CCC6)C(CNC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@@H](NC(CN)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)CC9=CC=C(C=C9)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC%10=CNC%11=CC=CC=C%10%11)=O)=O)=O)=O
Molecular Formula
C138H199N35O30
Molecular Weight
2828.27
References & Citations
[1]Crawley J N, et al. Galanin receptor antagonists M40 and C7 block galanin-induced feeding[J]. Brain research, 1993, 600 (2) : 268-272.|[2]Xu X J, et al. New high affinity peptide antagonists to the spinal galanin receptor[J]. British journal of pharmacology, 1995, 116 (3) : 2076-2080.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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