PF-06795071
PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].
Product Specifications
CAS Number
2075629-81-9
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/PF-06795071.html
Purity
99.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC[C@H](C(F)(F)F)OC(N1C[C@]([C@@]2([H])C1)([H])[C@H]2C3=NN(C4=CC=C(F)C=C4)C=C3)=O
Molecular Formula
C18H17F4N3O3
Molecular Weight
399.34
References & Citations
[1]McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61 (7) :3008-3026.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: 6A1]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fc01f/imageurl/am06515su-n.webp)
AM06515SU-N 100 µL
B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: 6A1]
Sign In for Pricing
View Details 
BNC682042-100 1x 100 µL
Human IgG4 (Ig Heavy Constant Gamma 4) (G4m Marker) (IGHG4/2042R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![B4GALNT4 Mouse Monoclonal Antibody [Clone ID: OTI7F2]](https://cdn.genprice.uk/products/937/68dd18bc061270361e9091da/imageurl/cf816146.webp)
CF816146 100 µg
B4GALNT4 Mouse Monoclonal Antibody [Clone ID: OTI7F2]
Sign In for Pricing
View Details