Thonzylamine (hydrochloride)

Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].

Product Specifications

CAS Number

[63-56-9]

Product Name Alternative

Neohetramine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/thonzylamine-hydrochloride.html

Smiles

COC(C=C1)=CC=C1CN(CCN(C)C)C2=NC=CC=N2.Cl

Molecular Formula

C16H23ClN4O

Molecular Weight

322.83

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27 (24) : 115127.|[2]AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59 (5) : 438-41.